What is Norditropin Pen 45iu and how is it used?

What is Norditropin Pen 45iu and how is it used?Norditropinis given by injection under the skin (subcutaneous) and is used to treat:children who are not growing because of low or no growth hormone.Norditropinis a prescription medicine that contains human growth hormone, the same growth hormone made by the human body.children who are short (in stature) and who have Noonan syndrome, Turner syndrome, or were born small (small for gestational age-SGA) and have not caught-up in growth by age 2 to 4 years.children who have Idiopathic Short Stature (ISS).children who are not growing who have Prader-Willi syndrome (PWS).adults who do not make enough growth hormone.What are the possible side effects of Norditropin?Norditropin may cause serious side effects, including:high risk of death in people who have critical illnesses because of heart or stomach surgery, trauma or serious breathing (respiratory) problems.high risk of sudden death in children with Prader-Willi syndrome who are severely obese or have breathing problems, including sleep apnea.increased risk of growth of cancer or a tumor that is already present and increased risk of the return of cancer or a tumor in people who were treated with radiation to the brain or head as children and who developed low growth hormone problems. Your or your child’s healthcare provider will need to monitor you or your child for a return of cancer or a tumor. Contact the healthcare provider if you or your child starts to have headaches, or have changes in behavior, changes in vision, or changes in moles, birthmarks, or the color of your skin.new or worsening high blood sugar (hyperglycemia) or diabetes. Your or your child’s blood sugar may need to be monitored during treatment with Norditropin.increase in pressure in the skull (intracranial hypertension). If you or your child has headaches, eye problems, nausea or vomiting, contact the healthcare provider.serious allergic reactions. Get medical help right away if you or your child has the following symptoms:swelling of your face, lips, mouth, or tonguetrouble breathingwheezingsevere itchingskin rashes, redness, or swellingdizziness or faintingfast heartbeat or pounding in your chestsweatingyour body holding too much fluid (fluid retention) such as swelling in the hands and feet, pain in your joints or muscles or nerve problems that cause pain, burning or tingling in the hands, arms, legs and feet. Fluid retention can happen in adults during treatment with Norditropin. Tell your healthcare provider if you have any of these signs or symptoms of fluid retention.decrease in a hormone called cortisol. The healthcare provider will do blood tests to check your or your child’s cortisol levels. Tell your or your child’s healthcare provider if you or your child has darkening of the skin, severe fatigue, dizziness, weakness, or weight loss.decrease in thyroid hormone levels. Decreased thyroid hormone levels may affect how well Norditropin works. The healthcare provider will do blood tests to check your or your child’s thyroid hormone levels.hip and knee pain or a limp in children (slipped capital femoral epiphysis)worsening of curvature of the spine (scoliosis)severe and constant abdominal pain. This could be a sign of pancreatitis. Tell your or your child’s healthcare provider if you or your child has any new abdominal pain.loss of fat and tissue weakness in the area of skin you inject. Talk to your healthcare provider about rotating the areas where you inject Norditropin.increase in phosphorus, alkaline phosphate and parathyroid hormone levels in your blood. Your or your child’s healthcare provider will do blood tests to check this.The most common side effects of Norditropin include:injection site reactions and rashesheadachesThese are not all the possible side effects of Norditropin.Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects to Novo Nordisk at 1- 888-668-6444.DESCRIPTIONNORDITROPIN(somatropin) for injection is a recombinant human growth hormone. It is a polypeptide of recombination DNA origin and is synthesized by a special strain of E. coli bacteria that has been modified by the addition of a plasmid which carries the gene for human growth hormone.NORDITROPIN contains the identical sequence of 191 amino acids constituting the naturally occurring pituitary human growth hormone with a molecular weight of about 22,000 Daltons.NORDITROPIN is supplied as a sterile solution for subcutaneous use in ready-to-administer pre filled pens with a volume of 1.5 mL or 3 mL.INDICATIONSPediatric PatientsNORDITROPIN is indicated for the treatment of pediatric patients with:growth failure due to inadequate secretion of endogenous growth hormone (GH),short stature associated with Noon an syndrome,short stature associated with Turner syndrome,short stature born small for gestational age (SGA) with no catch-up growth by age 2 years to 4 years of age,Idiopathic Short Stature (ISS), height standard deviation score (SDS)